Radiation induced CNS toxicity – molecular and cellular mechanisms
نویسندگان
چکیده
منابع مشابه
O14: Cellular and Molecular Mechanisms of Spinal Cord Trauma
لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملMolecular and cellular mechanisms for microbial entry into the CNS.
A number of pathogenic microbes including neuroinvasive viruses, bacteria and parasites are capable of entry into the central nervous system (CNS) and cause a variety of clinical manifestations. The cellular and molecular mechanisms for the CNS invasion have been extensively studied in the last two decades. Viruses invade neurons and thereby cause encephalitis or peripheral neuritis, while bact...
متن کاملThe Mechanisms of Radiation-Induced Bystander Effect
The radiation-induced bystander effect is the phenomenon which non-irradiated cells exhibit effects along with their different levels as a result of signals received from nearby irradiated cells. Responses of non-irradiated cells may include changes in process of translation, gene expression, cell proliferation, apoptosis and cells death. These changes are confirmed by results of some In-Vivo s...
متن کامل[Cellular and molecular mechanisms of radiation-induced brain injury: can peripheral markers be detected?].
Investigation of the mechanisms of radiation-induced brain injury is a relevant fundamental objective of radiobiology and neuroradiology. Damage to the healthy brain tissue is the key factor limiting the application of radiation therapy in patients with nervous systems neoplasms. Furthermore, postradiation brain injury can be clinically indiscernible from continued tumor growth and requires dif...
متن کاملMolecular, genetic and epigenetic pathways of peroxynitrite-induced cellular toxicity
Oxidative stress plays a key role in the pathogenesis of cancer and many metabolic diseases; therefore, an effective antioxidant therapy would be of great importance in these circumstances. Nevertheless, convincing randomized clinical trials revealed that antioxidant supplementations were not associated with significant reduction in incidence of cancer, chronic diseases and all-cause mortality....
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 2001
ISSN: 0007-0920,1532-1827
DOI: 10.1054/bjoc.2001.2100